Removed items are "deleted" or "reworked" items which were generally changed into a different item or aspect of the game. Many other items have also been removed since the Alpha. A list of the current information of these items can be found here.
Abyssal Scepter
Alacrity
Ancient Coin
Ancient Pocket Watch
Arcane Sweeper
Arcane Sweeper (Item)
Atma's Impaler
Atma's Reckoning
Avarice Blade
Bag of Tea
Banner of Command
Blackfire Torch
Blink Dagger
Bloodletter's Veil
Blue Pill
Brawler's Gloves
Breathstealer
Captain
Catalyst the Protector
Cloak and Dagger
Crystalline Flask
Deathfire Grasp
Defense Upgrades
Dervish Blade
Devourer
Distortion
Doran's Lost Blade
Doran's Lost Idol
Doran's Lost Ring
Doran's Lost Shield
Eleisa's Miracle
Elixir of Agility
Elixir of Brilliance
Elixir of Fortitude
Elixir of Ruin
Elixir of Skill
Emblem of Valor
Entropy
Explorer's Ward
Eye of the Equinox
Eye of the Oasis
Face of the Mountain
Farsight Orb
Feral Flare
Flesheater
Force of Nature
Frost Queen's Claim
Furor
Ghostwalkers
Giant Slayer
Globe of Trust
Gouging Blade
Greater Lens
Greater Orb
Greater Stealth Totem
Greater Totem
Greater Vision Totem
Grez's Spectral Lantern
Heart of Gold
Heart of Targon
Hunter's Potion
Ichor of Illumination
Ichor of Rage
Innervating Locket
Ionic Spark
Juggernaut
Kage's Lucky Pick
Kitae's Bloodrazor
Leviathan
Lifeline
Lightbringer
Looted Oracle's Extract
Lord Van Damm's Pillager
Madred's Bloodrazor
Madred's Razors
Magus
Malady
Mana Manipulator
Mana Potion
Mandrake Ward
Mariner's Vengeance
Marksman's Rifle
Martyr's Gambit
Meki Pendant
Mercenary Upgrades
Mirage Blade
Moonflair Spellblade
Murksphere
Netherstride Grimoire
Nomad's Medallion
Odyn's Veil
Offense Upgrades
Ohmwrecker
Oponn's Razor
Oracle's Elixir
Oracle's Hood
Oracle's Lens
Orb of Winter
Overlord's Bloodmail
Pathfinder's Knife
Peering Farsight Ward
Pendant of Zephiris
Philosopher's Medallion
Philosopher's Stone
Pilfered Health Potion
Pilfered Potion of Rouge
Pilfered Stealth Ward
Poacher's Dirk
Poacher's Knife
Pox Arcana
Pridestalker's Blade
Priscilla's Blessing
Prospector's Blade
Prospector's Ring
Puppeteer
Quill Coat
Ranger's Trailblazer
Raptor Cloak
Regrowth Pendant
Rejuvenation Potion
Remnant of the Ascended
Remnant of the Aspect
Remnant of the Watchers
Renewal Tunic
Rite of Ruin
Rite of Ruin
Runeglaive
Runegorger
Runic Bulwark
Sage's Ring
Sated Devourer
Scroll of Teleportation
Scrying Orb
Sightstone
Sly Sack of Gold
Soul Anchor
Soul Shroud
Soul Sickle
Spear of Shojin
Spectral Cutlass
Spellbreaker
Spirit Stone
Spirit of the Ancient Golem
Spirit of the Elder Lizard
Spirit of the Spectral Wraith
Staff of Flowing Water
Stark's Fervor
Stat-Stick of Stoicism
Stealth Ward (Item)
Sweeping Lens
Swindler's Orb
Sword of the Divine
Sword of the Occult
Talisman of Ascension
Targon's Brace
Teleport
The Brutalizer
The Golden Spatula
The Rose's Pride
Timeworn Ancient Coin
Timeworn Face of the Mountain
Timeworn Frost Queen's Claim
Timeworn Frostfang
Timeworn Nomad's Medallion
Timeworn Relic Shield
Timeworn Spellthief's Edge
Timeworn Talisman of Ascension
Timeworn Targon's Brace
Total Biscuit of Rejuvenation
Tracker's Knife
Travel Size Elixir of Iron
Travel Size Elixir of Sorcery
Travel Size Elixir of Wrath
Trickster's Glass
Typhoon Claws
Vision Ward
Wicked Hatchet
Will of the Ancients
Wizard's Regalia
Wooglet's Witchcap
Wriggle's Lantern
Yordle Stompers
Zeke's Harbinger
Zeke's Herald
Zephyr
Zhonya's Ring
Zz'Rot Portal
List of Items
Starter items
Potions and Consumables
Trinkets
Distributed items
Boots
Basic items
Epic items
Legendary items
Mythic items
Ornn's Mythic item upgrades
Champion exclusive items
Minion and Turret items
Removed items